Diagnosis of Primary Hyperparathyroidism (A Clinical Case)
https://doi.org/10.22448/AMJ.2025.2.51-55
Abstract
This article presents a clinical case of primary hyperparathyroidism in a 52-year-old female patient. In addition to classic clinical manifestations — hyperparathyroid osteodystrophy, nephrolithiasis, peptic ulcer disease, and multiple parathyroid adenomas — laboratory findings confirmed the diagnosis: elevated parathyroid hormone levels, increased total and ionized serum calcium, and decreased serum phosphate. Early diagnosis of hyperparathyroidism is often impeded by comorbid symptoms. Following comprehensive diagnostics, personalized treatment was initiated: parathyroidectomy followed by replacement therapy.
About the Authors
S. V. Naryshkina
Amur State Medical Academy, Ministry of Healthcare of the Russian Federation
Russian Federation
Russian Federation
Svetlana V. Naryshkina
Blagoveshchensk
O. A. Tanchenko
Amur State Medical Academy, Ministry of Healthcare of the Russian Federation
Russian Federation
Russian Federation
Olga A. Tanchenko
Blagoveshchensk
A. A. Shevchuk
Amur State Medical Academy, Ministry of Healthcare of the Russian Federation
Russian Federation
Russian Federation
Alina A. Shevchuk
Blagoveshchensk
References
1. Gorbacheva A.M., Pushkareva A.S., Eremkina A.K., et al. Clinical case of long-term unrecognized primary hyperparathyroidism. Russian Journal of Preventive Medicine. 2022; 25 (2): 74–80. DOI: https://doi.org/10.17116/profmed20222502174
2. Walsh J., Gittoes N., Selby P., Society for Endocrinology Endocrine Emergency Guidance: Emergency management of acute hypercalcaemia in adult patients // Endocrine Connections. 2016. Vol. 5, N 5. P. G9–G11. DOI: https://doi.org/10.1530/EC-16-0055
3. Dedov I.I., Melnichenko G.A., Mokrysheva N.G., et al. Draft of clinical guidelines for the diagnosis and treatment of primary hyperparathyroidism in adult patients. Endocrine Surgery. 2022; 16 (4): 5–54. DOI: https://doi.org/10.14341/serg12790
4. Mokrysheva N.G., Mirnaya S.S., Dobreva E.A., et al. Primary hyperparathyroidism in Russia according to the registry. Problems of Endocrinology. 2019; 65 (5): 300–310. DOI: https://doi.org/10.14341/probl10126
5. Garifullin A.I., Absaliamova R.M., Dubinina A.V., et al. Main parathyroid tumors. Endocrine Surgery. 2022; 16 (1): 4–12. DOI: https://doi.org/10.14341/serg12756
6. Walker M.D., Silverberg S.J. Primary hyperparathyroidism // Nature Reviews Endocrinology. 2018. Vol. 14, N 2. P. 115–25. DOI: https://doi.org/10.1038/NRENDO.2017.104
Review
For citations:
Naryshkina S.V., Tanchenko O.A., Shevchuk A.A. Diagnosis of Primary Hyperparathyroidism (A Clinical Case). Amur Medical Journal. 2025;13(2):51-55. (In Russ.) https://doi.org/10.22448/AMJ.2025.2.51-55
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