Сlinical features and prognosis criteria of bacterial pneumonia in patients with multiple myeloma
https://doi.org/10.24412/2311-5068-2023-11-2-13
Abstract
The purpose of the study was to study the characteristics of the course and prognosis criteria of bacterial pneumonia in patients with multiple myeloma. It has been estab-lished that pneumonia ranks second in the structure of infectious complications of multiple myeloma – 26%. Community-acquired pneumonia was diagnosed in 54% of cases, nosocomial pneumonia – in 46% of cases. The risk of pneumonia in multiple myeloma is associated with the following factors: renal failure, thrombocytopenia and severe hemorrhagic syndrome, ECOG status 3-4, relapse of multiple myeloma. In patients with renal failure and neutropenia, late nosocomial pneumonia occurred in low-symptomatic or latent variants. Early nosocomial pneumonia and Community-acquired pneumonia in multiple myeloma in most cases had a typical course. The causative agents of late nosocomial pneumonia in most cases were gram-negative flora, while Community-acquired pneumonia and Early nosocomial pneumonia were gram-positive. An unfavorable prognosis was asso-ciated with the following factors: status 3-4 on the ECOG scale, 3-4 degree of comorbidity on the CIRS scale for cardiovascular diseases, association of causative agents of pneumo-nia, severity of the condition more than 16 points. according to the APACHE II scale, la-tent variant of the course of NP, severe hemorrhagic syndrome, relapse of MM, bilateral lo-calization of the inflammatory process.
About the Authors
A. A. Sinyuk
Far Eastern Scientific Center for Physiology and Pathology of Respiration
Russian Federation
Russian Federation
Anastasija A. Sinyuk
Blagoveshchensk
V. V. Voitsekhovsky
Amur State Medical Academy
Russian Federation
Russian Federation
Valerij V. Voitsekhovsky
Blagoveshchensk
I. V. Yakimenko
Amur Regional Clinical Hospital
Russian Federation
Russian Federation
Irina V. Yakimenko
Blagoveshchensk
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For citations:
Sinyuk A.A., Voitsekhovsky V.V., Yakimenko I.V. Сlinical features and prognosis criteria of bacterial pneumonia in patients with multiple myeloma. Amur Medical Journal. 2023;11(2):13-23. (In Russ.) https://doi.org/10.24412/2311-5068-2023-11-2-13
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